Ongoing projects in the Bowdish lab:

1. Uncovering how age, frailty, and chronic inflammation alter immune responses to vaccination and infection.
2. Understanding why susceptibility to pneumonia increases with age and can accelerate or exacerbate age related health conditions such as cognitive decline.
3. Elucidating how the aging gut microbiome contributes to age-associated inflammation and frailty/unhealthy aging
4. Uncovering how age-associated inflammation alters the maturation and function of monocytes and macrophages.

General publications on macrophages:

1. Reviews, protocols, and publications on macrophages

Past projects in the Bowdish lab:

1. Discovering how age-related changes in the upper respiratory microbiota contribute to susceptibility to pneumonia
2. Characterizing the role of the macrophage scavenger receptors in host defence

(opens in a new