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Bowdish Lab

Macrophage Biology at McMaster University

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  • The Lab
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    • Vaccination and infection in older adults
    • Age, pneumonia, and post-pneumonia health issues
    • The role of the microbiota in healthy/unhealthy aging
    • Uncovering how age-associated inflammation alters the maturation and function of monocytes and macrophages.
    • General Macrophage Publications
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Antibody Production & Purification

Protein A Sepharose purification of Antibodies

  • This protocol is useful for purifying antibodies from hybridoma cultures and serum.

Immunization protocol for rabbits

  • This protocol is used for generating polyclonal antibodies to peptide ligands in rabbits.
  • Citation: Novakowski KE, et al.A naturally occurring transcript variant of MARCO reveals the SRCR domain is critical for function. Immunol Cell Biol. 2016 Aug;94(7):646-55.

Dawn Bowdish

Recent Lab News

  • The Bowdish lab is no longer accepting thesis student applications for the 2025/26 academic year.
  • Publication: Canadian Immunity Task Force (CITF) Hema-Net Serosurveillance Meeting
  • “The Perils of Being Born in the Fall” will be at the Zoetic Theatre November, 12, 2024
  • Dr. Bowdish speaks at the 2024 Innovation Nation Conference & Student Innovation Showcase
  • Dr. Bowdish discusses COVID-19 on The Agenda with Steve Paikin
  • Publication: Reassuring humoral and cellular immune responses to SARS-CoV-2 vaccination in participants with systemic sclerosis
  • Publication: “Monocyte-driven inflamm-aging reduces intestinal barrier function in females”
  • Podcast: Spreading awareness on peak asthma week
  • Publication: Chronic TNF in the aging microenvironment exacerbates Tet2 lost-of-function myeloid expansion
  • Dr. Bowdish will be performing at the 2024 Hamilton Fringe Festival

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